THREE POINTS. You are stutying a new kind of blbod ciatting disorder and fai tho
ID: 100062 • Letter: T
Question
THREE POINTS. You are stutying a new kind of blbod ciatting disorder and fai thot itis otyecal ingle gene, two allele dominant r cesstve kind oi disease. When you arolyze the diseisE in po f young adults you find it obeys the Harty We re e urn quation Yen fnd the Glowing genobype frequencies tn theseyaungds AAO 2and o-ao9 a) Calc alate the relative ftness vane for twie porlabi b) Yon now study an older population aud duacovtr thet t a reus lathal ona, Mou detervmine ue equiltibriu, fregwency of the hallela to oc o.Is for thus populattms suming that the fitness ofthe howseygou not change ss trey age.Explanation / Answer
AA= 0.49; Aa=0.42; aa=0.09
AA= 49%; Aa= 42% aa=9%
Highest reproductive success among the genotypes is for AA i.e. 49%
Wed divide the genotypic frequencies with highest frequency, we get relative fitness for each phenotype.
AA=1 as 49/49
Aa=42/49 = 0.85
aa=9/49= 0.18
As the gentic frequency of only aa changes, the relative fitness of only aa will change. It will be now 15/49=0.3
0.18(1-s)=0.3 where S is the selection coefficient
by rearranging,
0.18-0.18s=0.3
0.18s= 0.12
s=0.12/0.18=0.67
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