Chose the best answer for the following questions. Which of the following amino

Question

Chose the best answer for the following questions. Which of the following amino acid is most likely to disrupt a alpha- helix structure? Val. Pro. Trp. Glu. Arg. Which of the following has layered beta-sheet structure. Fibroin a-kratin globins collagen none of these Which of the following is the best to describe hemoglobin: a domain a motif a protein with a quaternary structure a protein with a tertiary structure none of the above. Which of the following would contribute to the stability tertiary structure? charge-charge interaction between lysine and aspartic acid disulfide bond hydrogen bond between serine hydroxyl group and amide of glutamine hydrophobic interaction between leucine and valine all of the above Which of the following is the major force that stabilizes the secondary structure of proteins? charge-dipole interaction. dipole-dipole interaction dipole-induced dipole interaction. London dispersion force. hydrogen bonding Which of the f

Explanation / Answer

1. Proline is the amino acid which desurpts the alpha helix structre it also desruptts beta sheeted structure also.Due to its ide chain consraints and sterics it becomes incompatable with the helix.

2. Fibroin is the protein which has layered beta- sheet structure.

3. Haemoglobin is a protein with a quaternary structure.

4. all the above contribute to the contibute to the stability of tertiary structure of proteins including Hydrophobic interactions, Disulfide bridges, Hydrogen bonding and charge charge interaction..

5. Major force influencing the stability of secondary structure of a protein is Hydrogen Bonding.

6. Amino acid Tryptophan contributes to the UV absor[tion of protein.

7. D) It iis a biological molecule like amylos is incorrectb statement because amylose is polysaccharide made up of alpha d glucose bound together by glycosideic bonds where as amyloid is an aggregation of proteins.

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