You have become increaslinly concerned about the expansion of antibacterial resi
ID: 100824 • Letter: Y
Question
You have become increaslinly concerned about the expansion of antibacterial resistance in human pathogens. As a result you would like to establish a pharmaceutical start-up company to counteract the spread of antibiotic resistance. In researching more you've learned that sometimes antibiotic resistanece is spread in a person taht is simulaneously infected with two different pathogenic species. Propose 2 proteins taht could potentially be good targets to prevent the spread of anitbiotic resistance in a person with a double infection.
Explanation / Answer
Ans- there are 7 types of proteins on the surface of pathogens which aquire resistance namely OM , Tol c , Ompt , Fid1 , Ompw, Lamb and Dps
The upside regulated protein deletion increase antibiotics suspectiblity and decrease antibiotics resistance.
The two important target protein are Om, Tolc. Deletion of these protein will help to decrease antibiotics resistance.
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