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Which of these statements is generally true of integral membrane proteins? A. Th

ID: 1014593 • Letter: W

Question

Which of these statements is generally true of integral membrane proteins?

A. The secondary structure in the transmembrane region consists solely of -helices or -sheets.

B.The domains that protrude on the cytoplasmic face of the plasma membrane nearly always have covalently attached oligosaccharides

C. They are unusually susceptible to degradation by trypsin.

D. They can be removed from the membrane with high salt or mild denaturing agents.

E. They undergo constant rotational motion that moves a given domain from the outer face of a membrane to the inner face and then back to the outer.

Amphipathic -helical structures

A. are composed of only hydrophobic amino acids.

B. can form a hydrophilic pore within a lipid bilayer

C. are positioned in the membrane with the polar amino acid R-groups in contact with the fatty acid tails of the lipid bilayer.

D. are destabilized by the hydrophobic environment of the lipid bilayer.

Explanation / Answer

A. The secondary structure in the transmembrane region consists solely of -helices or -sheets.

The secondary protein structure consists of -helices or -sheets.

C. are positioned in the membrane with the polar amino acid R-groups in contact with the fatty acid tails of the lipid bilayer.

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