1. True or False: a. Many tumor suppressor genes are involved in the detection a

Question

1.      True or False:

a.      Many tumor suppressor genes are involved in the detection and repair of DNA damage.

b.      Protein kinases are proteins that add phosphates to other proteins

c.       Cyclins are kinases.

d.      Cyclins are targeted for destruction through ubiquination.

e.      A gene encoding a DNA repair enzyme would be an example of a protooncogene.

f.        Once mitosis begins, checkpoint control does not occur until the cell reenters G1.

g.      Proteases in the caspase family are responsible for the destruction of cyclin-Cdk.

h.      Different cyclin-Cdks are responsible for triggering different stages of the cell cycle.

Explanation / Answer

Answer:

1.      True or False:

a.      Many tumor suppressor genes are involved in the detection and repair of DNA damage - TRUE

b.      Protein kinases are proteins that add phosphates to other proteins - TRUE

c.       Cyclins are kinases - FALSE (cyclins are regulatory proteins and regulate the cell cycle progression)

d.      Cyclins are targeted for destruction through ubiquination - TRUE

e.      A gene encoding a DNA repair enzyme would be an example of a protooncogene - FALSE (A gene encoding a DNA repair enzyme would be a tumor suppressor gene)

f.        Once mitosis begins, checkpoint control does not occur until the cell reenters G1 - FALSE

g.      Proteases in the caspase family are responsible for the destruction of cyclin-Cdk

h.      Different cyclin-Cdks are responsible for triggering different stages of the cell cycle - TRUE (different Cdks are used at diferent stages of cell cycle progression)

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