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O 9/2/2016 06:00 PM A 10.9/20 Gradebook Calculator Periodic Table Print Question

ID: 1023841 • Letter: O

Question

O 9/2/2016 06:00 PM A 10.9/20 Gradebook Calculator Periodic Table Print Question 17 of 29 Map A Sapling Learning The pKa of the a-carboxyl group of serine is 2.21, and the pKa of its a amino group is 9.15. Calculate the average net charge on serine if it is in a solution that has a pH of 8.10. If the charge is positive, do not enter a sign. Number Next E Give Up & View Solution Check Answer Previous xit 8 Hint Start with the Henderson-Hasselbalch equation. pH-pKa log HA The pH and pKa are given in the question. Consider which pKa value should be used in the equation. Note that this is not the charge of the predominant species at this pH, but the average charge on the amino acid. The answer is not a whole number.

Explanation / Answer

Net charge is defined as the average value of the pKa values of the components.

Net charge = (2.21+9.15)/2

= 5.68