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Sapling Learning Map Ase is an enzyme that cleaves the P-05 bond in RNA. It has

ID: 1031619 • Letter: S

Question

Sapling Learning Map Ase is an enzyme that cleaves the P-05 bond in RNA. It has two His residues in the active site. Suggest a plausible explanation why the enzyme activity changes when pH is increased or decreased from -pH 6.0 as shown in the graph below 120 100 80 60 40 Data provided by Dr. Sunita Chowrira, University of British Columbia. 20 8 10 Choose all the true statements Both His residues are deprotonated at pH higher than than 6.5 The RNAse reaction is an example of metal ion catalysis with a positively charged metal There are two His residues, and both are deprotonated below pH 4.2 RNAse is an acid-base catalyst The substrate is affected by the change in pH, and is inactive (+ charged) when pH is abo Incorrect

Explanation / Answer

a) RNA as is an acid calalyst.

b)the substrate is affected by the change in ph and is unaffective for me

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