Which of the following statements accurately describe the role of lactate dehydr

Question

Which of the following statements accurately describe the role of lactate dehydrogenase in human biology? Mark all that are correct.

A. Lactate dehydrogenase automatically converts pyruvate to lactate whenever levels of NADH and pyruvate are high.

B. Lactate dehydrogenase allows for energy generation with no net oxidation of carbon.

C. The regeneration of NAD by lactate dehydrogenase allows the Krebs Cycle to deliver electrons to complex I more quickly.

D. Lactate dehydrogenase allows glycolysis to produce NADH at a faster rate than the rate at which the ETC can accept NADH electrons.

Explanation / Answer

Human lactate dehydrogenase (hLDH5), a glycolytic enzyme responsible for the conversion of pyruvate to lactate coupled with oxidation of NADH to NAD+, plays a crucial role in the promotion of glycolysis in invasive tumor.

so the option is A. Lactate dehydrogenase automatically converts pyruvate to lactate whenever levels of NADH and pyruvate are high.

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