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1. Read and understand Lab 1 Study Guide to rationalize the stability of cyclopr

ID: 1045014 • Letter: 1

Question

1. Read and understand Lab 1 Study Guide to rationalize the stability of cyclopropane, cyclobutane, and cyclopentane. (5 points) 2. Look at the Acid-Base Extraction study guide. Be able to reproduce a flow-chart for the separation of 4 compounds similar to the one on that study guide (amine, carboxylic acid, phenol, and somee aromatic compound), understand why any of the compound(s) is in the aqueous layer while the other(s) is in the organic layer, and understand the meaning of density and why it governs top/ bottom layer. (5 points) 3. Study the TLC pre-lab quiz and be able to calculate the RE values. You don't need to show the full calculations and answer, just setting up the correct values in the equation is sufficient. (5 points) 4. Be able to describe spectroscopic techniques (13C NMR, H NMR, & IR) for the characterization of isoborneol to camphor. (1.67 points each, 5 points total) 5. Be able to show a plausible mechanism for addition of bromine to trans-cinnamic acid Classify as anti-addition, carbocation intermediate, or syn-addition. (5 points total) 6. Study the Alkyl Halides and Nucleophilic Substitution lab. Be able to explain why a reaction is faster in acetone but slower in ethanol. Be able to explain the role of each reagent in the reaction (ie', explain what silver nitrate is doing in the reaction). Be able to explain lab procedures, i.e what happens if my test tube isn't fully dry, etc.

Explanation / Answer

Cyclopentane >cyclobutane >cyclopropane

Stability order

If we see angle of normal alkane that is 109.5 . But in case of cyclopentane 108 , cyclobutane 90 degree ,cyclopropane 60 degree .

Incrising deviation in angle , lead angle strain and decrease stability.