THREE CLINICAL CHEMISTRY QUESTIONS: 1. During the first morning analyzer run, th

Question

THREE CLINICAL CHEMISTRY QUESTIONS:

1.     During the first morning analyzer run, the chemistry tech notices that QC 1 for Uric Acid is 3.8mg/dL and QC 2= 5.2mg/dL. QC 1 = 3.2-4.2mg/dL; QC 2= 6.0-7.4mg/dL at 95% confidence levels. Using this information, what Westgard rule has been violated?         

a.     None

b.     1 (3S)

c.     2 (2S)

d.     4 (1S)

2.     A 95% confidence limit for cholesterol precision is 190-210 mg/dL. The coefficient of variation for this methodology is:

a.     1.25%

b.     2.5%

c.     5.0%

d.     7.5%

3.     A 6.0 g/dL albumin standard has a measured absorbance of 0.900 in a reaction with Bromcresol Green measured at 628 nm. A control whose absorbance is 0.600 has a concentration of:

a.     2.0 g/dL

b.     4.0 g/dL

c.     7.0 g/dL

d.     9.0 g/dL

Explanation / Answer

3.     A 6.0 g/dL albumin standard has a measured absorbance of 0.900 in a reaction with Bromcresol Green measured at 628 nm. A control whose absorbance is 0.600 has a concentration of:

b.     4.0 g/dL

Beer's law (=====Absorbance = e L c)

C1 / C2 = A1 / A2

6.0 g/Dl / C2 = 0.900  / 0.600

C2 =[6.0 x   0.600] /0.900  =4.0 g/dL-----------answer

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