True and False 7-TM receptors usually transmit their signal via a G-protein ___

Question

True and False 7-TM receptors usually transmit their signal via a G-protein ___ CAMP phosphodiesterase plays a part in terminating the insulin response _____ Protein kinase a plays a part in transmitting the epinephrine signal ______ IP3 receptors involve tyrosine kinases ____ IP3 receptors involve calcium _____ Growth hormone receptor is of the 7-TM type ____ Some tyrosine kinase receptors involve G-proteins _____ Most tyrosine C is involved with the epidermal growth factor receptor ____ Ras is a type of protein kinase ____ PIP3 is involved in transmitting the insulin signal ____ Akt is also called protein kinase B. Akt deactivates GLUT-4 transporters _____ Oncogenes usually express molecules used in signal transduction ____ Cyclic AMP is used in transmitting the insulin signal ____

Explanation / Answer

1 true

2 false

3 true

4 true

5 true

6 true

7 true

8 true

9 false

10 true

11 true

12 true

13 true

14 true

15 true

G protein coupled receptors

1. The receptor is generally a 7tm protein (7 pass)

2. The receptor demonstrations through a G protein (trimeric GTP restricting protein)

3. This G protein will direct the movement of a different plasma layer bound target compound or particle channel.

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nositol trisphosphate or inositol 1,4,5-trisphosphate (likewise usually known as triphosphoinositol; abridged InsP3 or Ins3P or IP3), together with diacylglycerol (DAG), is an auxiliary flag-bearer atom utilized as a part of flag transduction and lipid motioning in organic cells. While DAG remains inside the film, IP3 is solvent and diffuses through the cell. It is made by hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2), a phospholipid that is situated in the plasma layer, by phospholipase C (PLC

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flag transduction pathways including the Raf proto-oncogene. ... It is initiated in light of a wide assortment of extracellular boosts, for example, insulin, nerve development calculate (NGF), platelet inferred development consider (PDGF), and because of articulation of oncogenes, v-src and v-ras, in a cell-particular way.

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