(so people can query...) Under conditions where ketone bodies are being produced

Question

(so people can query...)

Under conditions where ketone bodies are being produced in the liver, how many ATPs can be produced from a molecule of palmitic acid if all resulting molecules of acetyl-CoA are converted into ?-hydroxybutyrate?

Can someone break this down? Thanks...

Problem 16.6 Part A Under conditions where ketone bodies are being produced in the liver, how many ATPs can be produced from a molecule of palmitic acid if all resulting molecules of acetyl-CoA are converted into B-hydroxybutyrate? Express your answer using one decimal place. Net yield 16.0 ATP Submit My Answers Give Up All attempts used; correct answer displayed Provide Feedback Continue

Explanation / Answer

There are 16 carbons in palmitic acid so it will undergo 7 cycles of beta oxidation to produce 8 acetyl Co-A.

It will also give 7 NADH and 7 FADH2 during oxidation

Now each acetyl coA will further give : 3 NADH and 1 FADH2 and1 GTP

Total NADH from each palmitic acid = 7 + 3 X 8 = 31 NADH

ATPs from NADH = 3 X 31 = 93 ATPs

Total FADH2 = 8 + 7 = 15

ATPs from FADH2 = 15 x 2 = 30

ATPs as GTPs = 8

Total ATP = 131

We need two ATPs for activation of palmitic acid

so net ATP released = 131 - 2 = 129

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