Q12: Suppose you are attempting to separate the four (4) compounds listed below

Question

Q12: Suppose you are attempting to separate the four (4) compounds listed below using column chromatography. In a perfect scenario, in what order will these compounds elute from the column?

Fill in the Blank - Only write the capital letter designated each compound, i.e. A or B or C or D, in the answer blanks below.

Question 12 2 pts Suppose you are attempting to separate the four (4) compounds listed below using column chromatography. In a perfect scenario, in what order will these compounds elute from the column? 0 OH OH Fill in the Blank - Only write the capital letter designated each compound, i.e A or B or C or D, in the answer blanks below elutes first, then followed by , and finally comes off the column last

Explanation / Answer

In column chromatography the stationary phase is polar.

So polar compounds are attracted by polar stationary phase and going move slowly. So polar compounds are elutes last.

Nonpolar compounds are not attracted by the stationary phase. So nonpolar compounds moves lastly. Hence nonpolar compounds comes first.

Increasing Polarity order of given functional groups as follows:

Alkanes (A) < ketones (C) < alcohols (D) < carboxylic acids (B)

Less polar. More polar

The eluting order is A first, C second D third and B fourth.

A elutes first, then C , followed by D , and finally B comes of the column last.

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