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Question 1: (10 pts) Determine if the following statements are TRUE of FALSE The

ID: 1086560 • Letter: Q

Question

Question 1: (10 pts) Determine if the following statements are TRUE of FALSE The rate determining step in the addition of HA to an alkene is the addition of the proton. The addition of a proton to an alkene produces the most stable carbocation intermediate. Electrophilic addition to a conjugated diene takes place under kinetic control at room temperature temperatures. A carbene is characterized by an uncharged carbon atom that possesses a lone pair of electrons In carbon tetrachloride, treatment of an alkene with a molecular halogen produces a halohydrin. Oxymercuration-Demercuration proceds through a mercuryium intermediate and results in in the addition of water to an alkene with anti-Markovnikov regiochemistry. In a hydroboration-oxidation reaction, water adds to an alkene in a syn fashion with Markovnikof regiochemistry, to produce an alcohol. A synthesis scheme is an abbreviated recipe that tells how starting material is converted into the particular target molecule. Often the choice of solvent has no a dramatic impact on the outcome of a reaction. Ccon - _ _ Retrosynthetic analysis streamlines the process of designing an organic synthesis. j

Explanation / Answer

A- true

B - true

C - true(as under kinetic condition the Energy of activation is low compared to the energy of activation of the thermodynamic controlled product)

D - false ( the carbene has the sextet electronic configuration.In singlet carbene there is a pair of electron but not in triplet carbene)

E - false ( as it simply results the reduction of the alkene to the alkane)

F - false ( this scheme actually follows the Markonikov regioselectivity as propene results by this scheme to 2-propanol)

G- flase ( this scheme actually follows the anti-Markonikov regioselectivity as propene results by this scheme to 1-propanol)

H - true

I - false ( for example in two different solvents the reactivity of nucleophile during a substituion reaction, changes dramatically due to different kind of solavtion in two different solvents)

J - false ( by this way we actually try to revert back to the most probable starting elements)

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