In whippets, wild-type dogs are skinny. A mutation in the myostatin gene causes

Question

In whippets, wild-type dogs are skinny. A mutation in the myostatin gene causes dogs to become more muscular. Dogs containing one copy of the mutant myostatin gene are medium-muscled; dogs in which both copies of the myostatin gene are mutant are highly-muscled. A dog breeder mates a wild-type skinny dog with a highly-muscled dog. He then self-crosses the resulting F1 progeny. What are the phenotypic ratio in the F2 progeny?

This question is an example of incomplete dominance.

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Explanation / Answer

wild-type dogs are skinny---DD

highly-muscled dog.========dd

medium-muscled---Dd

wild-type dogs are skinny---DD x highly-muscled dog.========dd

medium-muscled---Dd--F1 OFFSPRING

Dd--F1 OFFSPRING X      Dd--F1 OFFSPRING

GAMETES

D

d

D

DD skinny

Dd medium

d

Dd medium

Dd higly

Ratio -1:2:1

Genotypic Ratio -1:2:1

Phenotypic - Ratio -1:2:1

GAMETES

D

d

D

DD skinny

Dd medium

d

Dd medium

Dd higly

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