25) The principal dangers associated with the use of aminoglycoside are ototoxic

Question

25) The principal dangers associated with the use of aminoglycoside are ototoxicity and nephrotoxicity. A third adverse reaction resulting in respiratory paralysis is:
a) Synthesis of scetylcholin
b) Curare like neuromuscular blockage
c) Centrally acting skeletal muscle relaxation
d) Sympathomimetic action
e) Phagocytosis of carcinogen
26) Select the stage at which the membrane potential of an excitable cell is more negative than the resting potential.
a) Depolarization phase of action potential
b) Upstroke of action potential
c) Hypopolarization
d) Hyperpolarization
e) Critical firing level
27) The electrical potential that is necessary to exactly balance a concentration gradient or conversely, the concentration gradient necessary to exactly balance an electrical potential difference is best describes by:
a) Starling’s Law of the Heart or Skeletal Muscle
b) Nernst Equation
c) All or None Law
d) Law of Projection
e) Law of Forward Conduction
28) Considering the flow of fluids within the blood vessels, vasodilation with the IV administration of acetylcholing in pharmacological doses would lead to:
a) Greater peripheral resistance
b) Reduced peripheral resistance
c) No effect blood pressure
d) Increase in blood pressure
e) Grand Mal Epilepsy
29) Select the condition characterized by the stimulation of endogenous endoculease activity, which leads to cleavage of nuclear chromatin, and programmed cell death of single cells as a result of the activation of a genetically programmed pathway for elimination of unwanted cell population.
a) Necrosis (Peripheral)
b) Apoptosis
c) Edema
d) Gliosislpathologic calcification
e) Anemia (Sickle Cell)
30) A stimulus either fails to elicit an action potential (a subthreshold stimulus), or it produces a full size action potential. For this reason the action potential is:
a) Not propagated along the length of the cell
b) Sodium channel of membrane voltage regulated
c) ATPase of membrane
d) K channel of membrane
e) All or none response
31) The gradient of sodium ions and potassium ions across the plasma membranes of cells is established by:
a) Hyaluronic acidase
b) Electrogenic sodium, potassium ATPase pump
c) Choline esterase
d) Phosphodiesterase
e) Adenyl cyclase

Explanation / Answer

25) The principal dangers associated with the use of aminoglycoside are ototoxicity and nephrotoxicity. A third adverse reaction resulting in respiratory paralysis is:

a) Synthesis of scetylcholin
b) Curare like neuromuscular blockage
c) Centrally acting skeletal muscle relaxation
d) Sympathomimetic action
e) Phagocytosis of carcinogen
-------------------------------------
26) Select the stage at which the membrane potential of an excitable cell is more negative than the resting potential.
a) Depolarization phase of action potential
b) Upstroke of action potential
c) Hypopolarization
d) Hyperpolarization
e) Critical firing level
---------------------------------------
27) The electrical potential that is necessary to exactly balance a concentration gradient or conversely, the concentration gradient necessary to exactly balance an electrical potential difference is best describes by:
a) Starling’s Law of the Heart or Skeletal Muscle
b) Nernst Equation
c) All or None Law
d) Law of Projection
e) Law of Forward Conduction
-----------------------------------------
28) Considering the flow of fluids within the blood vessels, vasodilation with the IV administration of acetylcholing in pharmacological doses would lead to:
a) Greater peripheral resistance
b) Reduced peripheral resistance
c) No effect blood pressure
d) Increase in blood pressure
e) Grand Mal Epilepsy
---------------------------------------------
29) Select the condition characterized by the stimulation of endogenous endoculease activity, which leads to cleavage of nuclear chromatin, and programmed cell death of single cells as a result of the activation of a genetically programmed pathway for elimination of unwanted cell population.
a) Necrosis (Peripheral)
b) Apoptosis
c) Edema
d) Gliosislpathologic calcification
e) Anemia (Sickle Cell)
----------------------------------------------
30) A stimulus either fails to elicit an action potential (a subthreshold stimulus), or it produces a full size action potential. For this reason the action potential is:
a) Not propagated along the length of the cell
b) Sodium channel of membrane voltage regulated
c) ATPase of membrane
d) K channel of membrane
e) All or none response
----------------------------------------------
31) The gradient of sodium ions and potassium ions across the plasma membranes of cells is established by:
a) Hyaluronic acidase
b) Electrogenic sodium, potassium ATPase pump
c) Choline esterase
d) Phosphodiesterase
e) Adenyl cyclase

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