1-The following is a portion of an abstract from The Journal of Structural Biolo
ID: 12862 • Letter: 1
Question
1-The following is a portion of an abstract from The Journal of Structural Biology:
Although the ____________ of Paramecium is made up of many sets of more reduced stacks of
cisternae than those of many mammalian cells, the stacks in Paramecium always bear a close
relationship to a transitional element of the ER from which non-clathrin-coated transition
vesicles arise. In QF-DE replicas two networks of filaments are clearly shown; one is in this ER-
____________ transition zone and the other is on the trans side of the _____________ stack. The
network associated with the trans-______________ region links a number of vesicular elements.
The network in the transition zone spans the distance between the ER and the cis-cisterna of the
______________ stack and has branches extending to the coats of the enmeshed nonclathrincoated
transition vesicles.
Which term best fills in the blank?
a. Rough endoplasmic reticulum
b. Lysosome
c. Mitochondria
d. Chloroplasts
e. Golgi (apparatus)
2. Mitochondria
a. are prevalent in aerobically respiring bacteria.
b. are capable of both synthesizing and storing starch.
c. have many integral membrane proteins across their inner membrane.
d. rely entirely upon chromosomal genes for synthesis of needed proteins.
3. Mycobacterium tuberculosis trapped in a phagosome of a host cell is able to resist
degradation by the digestive enzymes of the lysosome upon formation of the phagolysosome. With this in mind, which events occur as M. tuberculosis “exploits the
system” and enters the host cell?
a. M. tuberculosis binds to an external receptor of a clathrin-coated pit.
b. Macropinocytosis
c. Caveolae, that contain M. tuberculosis, form.
d. Pseudopods form and surround M. tuberculosis.
4. Proteus mirabilis is a bacterium. It is Gram-negative and motile. Giardia intestinalis is a parastic, eukaryotic, motile protist. All of the following accurately compares / contraststhese two organisms EXCEPT?
a. Whereas Proteus mirabilis has an outer membrane characterized by LPS, Giardia intestinalis lacks this feature.
b. Whereas the DNA of Giardia intestinalis is packaged by wrapping around histone octamers to form nucleosomes, the DNA of Proteus mirabilis is packaged largely by supercoiling.
c. Infections caused by both Giardia intestinalis and Proteus mirabilis could be effectively treated using penicillin.
d. Whereas the flagella of Giardia intestinalis are composed of nine pairs of microtuble doublets, the flagella of Proteus mirabilis are composed of a basal body, hook and filament.
e. Unlike the flagella of Proteus mirabilis, the flagella of Giardia intestinalis are membrane-bound.
Explanation / Answer
The network in the transition zone spans the distance between the ER and the cis-cisterna of the
Golgi (apparatus)stack and has branches extending to the coats of the enmeshed nonclathrincoated
transition vesicles.
Which term best fills in the blank?
a. Rough endoplasmic reticulum
b. Lysosome
c. Mitochondria
d. Chloroplasts
e. Golgi (apparatus)
2. Mitochondria
a. are prevalent in aerobically respiring bacteria.
b. are capable of both synthesizing and storing starch.
c. have many integral membrane proteins across their inner membrane.
d. rely entirely upon chromosomal genes for synthesis of needed proteins.
3. Mycobacterium tuberculosis trapped in a phagosome of a host cell is able to resist
degradation by the digestive enzymes of the lysosome upon formation of the
phagolysosome. With this in mind, which events occur as M. tuberculosis “exploits the
system” and enters the host cell?
a. M. tuberculosis binds to an external receptor of a clathrin-coated pit.
b. Macropinocytosis
c. Caveolae, that contain M. tuberculosis, form.
d. Pseudopods form and surround M. tuberculosis.
4. Proteus mirabilis is a bacterium. It is Gram-negative and motile. Giardia intestinalis is a parastic, eukaryotic, motile protist. All of the following accurately compares / contraststhese two organisms EXCEPT?
a. Whereas Proteus mirabilis has an outer membrane characterized by LPS, Giardia
intestinalis lacks this feature.
b. Whereas the DNA of Giardia intestinalis is packaged by wrapping around histone
octamers to form nucleosomes, the DNA of Proteus mirabilis is packaged largely
by supercoiling.
c. Infections caused by both Giardia intestinalis and Proteus mirabilis could be
effectively treated using penicillin.
d. Whereas the flagella of Giardia intestinalis are composed of nine pairs of
microtuble doublets, the flagella of Proteus mirabilis are composed of a basal
body, hook and filament.
e. Unlike the flagella of Proteus mirabilis, the flagella of Giardia intestinalis are
membrane-bound.
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