) Mechanisms by which antibiotics kill or inhibit microbial growh are: a) Inhibi
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Question
) Mechanisms by which antibiotics kill or inhibit microbial growh are: a) Inhibition of cell wall synthesis b) Injry to cell membrane cInhibition of protein synthesis d) Inhibition ofDNA or RNA syntheis e) All of the above 2) The semisynthetic methicillin has the advantage of a) Being broad spectrum b) Being inactivaled by penicillinase only on prolonged usage c)Not being affected by penicillinase d) All of the above e) None of the above Which of the following interfere with cell wall synthesis? b) Tetracyclines c) Penicillin d) Bacitracin Only C and D above A rare but serious complication of chloramphenicol treatment is: a)Kidney damage b) Deafness due to damage to eighth cranial nerve e Anemia due to suppression of bone marrow cells Anemia due to destruction of circulating red blood cells e) None of the above 5 The development of drug resistance in a microorganism may be due to: aAbility of the organism to destroy the antibiotic b) Mutation that allows the organism to by-pass the sensitive step c) Sporulation d) All of the above e Only A and B above The synthesis of vitamins B and X by enterie bacteria provides an example: b) Symbiosis c) Opportunism d) Infection eSynergestic effect
Explanation / Answer
Answer
1.mechanisms by which antibiotics kill or inhibit microbial growth are
e] All of the above
explaination- Mechanisms by which antibiotics kill or inhibit microbial growth some inhibits by acting the events necessary for bacterial growth.Some inhibits DNA replication,some transcription ,some antibiotic prevents bacteria from making protein,some prevents the synthesis of cell wall.
for example- Antibiotics that inhibits the cell wall synthesis are
beta lactum e.g.Penicillin.
Antibiotics that inhibits the protein synthesis are -example- Chloramphenicol,erythromycin.
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2. The semisynthetic methicillin has the advantage of
c]Not being affected by penicillinase
explaination-Methicillin is a semisymthetic derivative of penicillin.was developed as a type of antibiotic called a penicillinase-resistant penicillin and mdash.it contained a modification to the original penicillin structure that made it resistant to bacterial enzyme penicillinase(beta lactamase).
This enzyme is mostly produced by stephalococcus and disrupts certain types of penicillin by hydrolyzing the beta lactam ring.
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3] The following is interfere with the cell wall synthesis
c]Penicillin
Explaination- Penicillin work by inhibiting the final step of peptidoglycan synthesis which prevents transpeptidation (crosslinking) of the peptidoglycan molecules this leads to the death of the bacterium by osmotic pressure due to the loss of cell wall
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