please answer all the questions answering only one question is not helpful. Ques
ID: 132781 • Letter: P
Question
please answer all the questions answering only one question is not helpful.
Question 1
0 / 1 pts
Which of the following would most reliably suggest that a genomic sequence is functionally important?
Multispecies conservation of the sequence
Low copy number variation of the sequence
The presence of active chromatin marks over the sequence
The presence of a long open reading frame in the sequence
IncorrectQuestion 4
0 / 1 pts
Polytene chromosomes are useful for studying chromatin because they …
have distinct visible banding patterns.
are smaller than regular chromosomes and easier to manipulate.
can make polyploid cells.
lack heterochromatin.
All of the above.
IncorrectQuestion 5
0 / 1 pts
All of the “ultraconserved” elements found in the human genome have been shown to encode long noncoding RNAs.
True
False
IncorrectQuestion 6
0 / 1 pts
Upon heavy damage to the cell's DNA, the normal replicative DNA polymerases may stall when encountering damaged DNA, triggering the use of backup translesion polymerases. These backup polymerases ...
lack 3'-to-5' exonucleolytic proofreading activity.
are replaced by the replicative polymerases after adding only a few nucleotides.
can create mutations even on undamaged DNA.
may recognize specific DNA damage and add the appropriate nucleotide to restore the original sequence.
All of the above.
IncorrectQuestion 7
0 / 1 pts
Which of the following is true regarding retroviral-like retrotransposons?
They encode both a reverse transcriptase and an RNA polymerase.
They have directly repeated long terminal repeats at their two ends when integrated into chromosomal DNA.
Their genomic RNA can be translated to produce viral coat proteins.
They leave double-strand breaks in the original donor DNA.
The Alu element in our genome is an example of retroviral-like retrotransposons.
IncorrectQuestion 8
0 / 1 pts
DNA-only transposons ...
can be recognized by the presence of short inverted repeats at each end.
often encode a transposase that mediates the transposition process.
leave double-strand breaks in the donor chromosome.
can move by a cut-and-paste mechanism.
All of the above.
IncorrectQuestion 9
0 / 1 pts
In the research paper, the author used BrdU
to visualize where dividing cells are
to allow for incorporation into the DNA during synthesis
because she worked with squid, and since not many people worked with squid there are not many antibodies for squids
All of the above
IncorrectQuestion 10
0 / 1 pts
Some of the side effects of using lipophillic dies for lineage tracing experiments is,
you do not need to make a transgenic but can look at a cell immediately
the lipophillic dye can spread to any neighboring cell or future daughter cell
the cell can leave a trail behind itself as it moves through an organism which can confound data
all of the above
Explanation / Answer
Question 1. The answer is: Multispecies conservation of the sequence
Multispecies conservation of a genomic sequence is a strong indication of its functional importance.
Question 4. The answer is: have distinct visible banding patterns.
The enormous polytene chromosomes have proven very useful in visualizing chromosome organization; they can be readily studied by light microscopy and show distinct banding patterns corresponding to certain genomic positions, providing clues as to how the chromatin is organized into domains at a large scale.
Question 5. False
Although some of the ultraconserved elements may encode long noncoding RNAs, the function of the majority of these elements is still a mystery.
Question 6. The answer is: All of the above.
Question 8. The answer is: All of the above.
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