| Question 40 2 pts Testosterone is a lipophilic (hydrophobic) hormone. This is

Question

| Question 40 2 pts Testosterone is a lipophilic (hydrophobic) hormone. This is responsible for changes during this puberty: facial and pubic hair gr . h. ?ncreased muscle mass, and even undesired effects such as ao. Testosterone works by activating recei which then lead to of proteins involved in hair growth, muscle mass increase, etc. O intracellular receptors, transcription of genes that code for O cell-surface receptors,transcription of genes that code for O intracellular receptors, phosphorylation of O cell-surface receptors, phosphorylation of

Explanation / Answer

Testosterones are transported into the cytoplasm where it binds to the androgen receptor. Sometimes, these testosterones are reduced to 5?-dihydrotestosterone also known as DHT by 5?-reductase enzyme. These DHTs binds to the same androgen receptor and are known to be even more strongly binding than testosterone. These receptor complex further undergoes a structural change which further allows it to move into the nucleus of the cell. They further act as transciption factors and bind directly to specific regions on DNA. The areas of binding are called as hormone response elements (HREs) which further influences the transcriptional activity of certain genes thereby producing the androgen effects. Hence, testosterones binds to inter-cellular recpetors and transcribes genes that code for proteins responsible in hair growth.

answer: intracellular receptors, transcription of genes that code for

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