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Which of the Sollowing is NOT an example of epistasis? a lentil coat pattern b.

ID: 135271 • Letter: W

Question

Which of the Sollowing is NOT an example of epistasis? a lentil coat pattern b. quash fruit color e. sweet pea flower color Labrador retriever coat color e all of the above are examples of epistasis 9. Multiple endocrine neoplasia type 1 is caused by mutations in the MENI gene. Approximately 79% of individuals with this mutation exhibit this disorder by age 10. This is an example of h expressivity e more than one of the above 10. In chickens, the frizzle feather trait (it's a thing, look it upl) has been traced to mutation in a keratin gene. The frizzle feather mutation is also linked to increase metabolism. This is an example of a. multiple alleles b. quantitative traits d. pleiotropy 11. The theoretical maximum recombination frequency between two linked genes is 25% b.50% c.75% d.100% 12. Which of the following conditions is NOT X-linked in humans? b. classical hemophilia c. male pattern Saldncss d. Duchenne muscular dystrophy e all of the above are X-linked Which of the following conditions is NOT caused by nondisjunction? a. Down syndrome 13. b. Turner syndrome c. Klinefelter syndrome d. Marfan syndrome e. all of the above are caused by nondisjunction 14. Crossing over (recombination) occurs b. c. d. only in meiosis only in mitosis predominantly in meiosis predominantly in mitosis

Explanation / Answer

8] Option- [ C] sweet pea flower colour

The colour of the flower in sweet pea is determined by a single gene.

9] Option [ a] penetrance

Penetrance is the genetics is the proportion of individuals carrying a particular variant. So in the above case the disease has 75% penetrance.

10] Option [ d] pleiotropy

It is a condition when a single gene controls two or more apparently unrelated effects. So, the frizzle feather and increasd metabolism are controlled by a single gene.

11] Option [ d] 100%

When two genes are close together on the same chromosome i.e. they are linked, they do not assort independently and hence their maximum recombinant frequency can be 100% .

12] Option [e] all of the above are X-linked

13] Option [d] Mafran syndrome

It is caused by a mutation in the gene that determines the structure of fibrillin-1 a protein that forms connective tissue.

All other conditions are caused by an abnormal number of chromosomes resulting from non-disjunction.

14] Option [a] only in meiosis

Crossing over or recombination of genes occurs during the prophase of Meiosis 1 when the sister chromatids of homologous chromosomes exchange genetic materials.

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