Natasha was certain she was looking younger despite her 58 years on this Earth.

Question

Natasha was certain she was looking younger despite her 58 years on this Earth. Every day in the mirror her lines seemed to disappear. She had searched so long for something to slow the process ofaging her marriage depended on it! Vladimir would never stay with her if he saw the wrinkles she did! Even her precious parrot, Bruno, had noticed and shied away from her! She could never live without him so she tried it all: mercury creams, Botox, weight pills from the ancient woman in the south side market of Moscow, Switzerland's best cell therapy, and one pint of honey and another of yogurt every day But a week or two after her "youth came back she wasn't feeling nearly so good. Finally she went to the hospital because her fever was so high (102.8). She also had a non-stop horrible cough, muscle aches, vomiting, diarrhea, and a terrible headache. As the attendant physician at the hospital you try to narrow it down based on the patient profile, potential exposures and 1) What are the top five suspects for Natasha's infectious disease? Justify your choices. (10 points) 2) You send off for some laboratory tests right away and find the information below. Explain these results. Does this change your diagnosis? Ifso how? (6 points) b. Platelets-700,000/ L c. RBC-450,000,00O/L d. Hb-14g/dL e. HCT%-49 Bilirubin-6 mg/dL 8 Creatinine-097 mg/dL. 3) Natasha's cough got worse and worse and the clock seemed to be ticking. The results of the molecular and immunological panel are below. Has your reasoning been confirmed? Interpret them and describe how they work. (12 points) Western immunoblotting (first lane ladder,second Natasha's blood, third positive control, fourth negative control) a. LPS 240 KDa 83149 antigen 208 KDa FlaA-99 KDa

Explanation / Answer

1) The top 5 suspects of Natasha's infectious disease are,

Natasha had botox injections, cell therapy and taken a pint of honey and yoghurt. All these carry the risk of tetanus and hepatitis B infection. Her symptoms of high fever and leucocytosis points to the possibility of tuberculosis, typhoid and pertussis.

2) The laboratory results show an increased leucocyte and platelet count along with raised bilirubin levels. This points to the involvement if liver in the disease pathology. So, our diagnosis could be narrowed down to hepatitis B and hepatitis C.

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