13. A non-Golgi protein that reaches the TGN and has ncither a lysoscenal uag, n

Question

13. A non-Golgi protein that reaches the TGN and has ncither a lysoscenal uag, nor n will probably be 14. For the tagging of lysosomal peoteins, the mannose is phosphory lated in the 15. Secreted proteins are enclosed in vesicles in the TGN P 331 16. During endocytosis,the membrane of the endocytic vesicle i dcrived from the pkima ebo 17. Pinosytosis refers to the engulfiment of Pid and maccemoleco les Slide 3118. During phagocytosis, the cell extendspsadp o surround the particle. 19. Endocytic vesicles resulting from phagocytosis are cal 20. During receptor-mediated endocytosis, membrane curvature and invagination is promoted by adapeor protein and Clathcin and dunamin 21. During receptor-mediated endocytosis, the separation of the formed vesicle from the plasma membrane is promoted by 22. During vesicle trafficking, the recognition between the vesicle and the target membrane is mediated and by, 23, Worn-out organelles are digested after they have been enveloped into vacuoles. 24. In microtubules (MTs), a single stack of tubulin dimers is called a lasmicmicrestubules during 25. The microtubules found in cilia and flagella are called The first step in microtubule formation is called Aucea which dimers aggregate in oligomers? 26. The fint step in microtubule formation s calleducication nothan the critical concentration 27. If the prevailing tubulin concentration is (CC), the microtubules will grow

Explanation / Answer

13.From Trans Golgi Network (TGN) proteins are transported through three main pathways

14. Synthesis of Mannose 6 Phosphate (M-6-p)

Two steps

15. Secretory proteins are concentrated and stored in special secretory vessicles which are otherwise called secretory granules.

21. Membrane binding and fission proteins like dynamin and bar domain proteins helps in separating the formed vessicles from the plasma membrane during receptor mediated endocytosis which is a process by which cells take in substances like hormones through clathrin coated vessicles.

22. During vesicle trafficking, molecules like hormones are transported between synthesising locations and release locations. The vesicle surface membrane recognises the target surface membrane through special proteins called SNARE. V SNARE on vesicle recognises T SNARE on the target membrane.

23.Worn out organelles are envelpoed within membrane lined vacuoles tinto which several lysosomes can discharge their contents.

The contents like powerful enzymes are discharged by lysosomes which will now digest the worn out organelles.

Question number 9 in page 2. Molecules targeted to lysosomes are labelled with mannose 6 phosphate.

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