Name Section Name Section Name SectionName Section There is an outbreak of measl
ID: 136164 • Letter: N
Question
Name Section Name Section Name SectionName Section There is an outbreak of measles in a school in your area. displaying potential symptoms of measles. You are given two serum samples from child #1 and # both samples on ELISAs against measles virus. You don't know the samples were obtained at 7 days and 13 days after the outbreak began. Some parents are worried about their kids, who have been 2 and are told to run patient history of either, but you do know the at 7 days 81 at 7 days 000000000%OOOOOOOOOOOO lgM #2at 12 days #1 at 12 days lgM what can you tell me about each patient? which one(s) is/are in real danger of infection: Child #1 and/or Child Explain your reasoning by discussing IlgG vs. lgM production and patient history. (no fluff...just facts)Explanation / Answer
Elisa test done on two children on day 7 and day 12
Measles is self resolving infection within 10 to 12 days
Child 1 at day 7 igM production and igG production both present
Positive IgM and IgG tests for antibodies detected in an initial blood sample mean that it is likely that the person became infected with virus within recent weeks. ... If the IgG is positive but the IgM is low or negative, then it is likely that the person had an infection sometime in the past.
Child 2 has igM more than igG means he has active infection therefore both are infected but children 2 have active infection
Both igG IgM are produced in primary immune response
IgM peaks in 7 to 10 days and decrease rapidly and in 4 to 6 weeks become undetecteble
IgG production peaks in 4 weeks and persist lifelong giving lifelong immunity
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