Numerous clinical studies have confirmed the link between age-dependent atherosc

Question

Numerous clinical studies have confirmed the link between age-dependent atherosclerosis and elevated serum LDL levels. Many pharmaceutical companies have therefore developed drugs, known as statins, that can be used to lower serum LDL levels as a treatment for atherosclerosis. The first generation of these drugs was designed to inhibit the activity of HMG-CoA reductase. What additional activity that is stimulated by statins also contributes to reduced levels of serum LDL?

Choose one:

A. increased LDL endocytosis

B. decreased synthesis of steroid hormones

C. decreased synthesis of bile acids

D. increased HDL levels

Explanation / Answer

Statins inhibit the activity of HMG-CoA reductase as well as it increase the HDL levels.HDL is known as Good Cholesterol.It takes excess cholesterol to liver and break it down and lower the risk of Atherosclerosis.

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