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3. There are over 17,000 base pairs on chromosome 17 that code for a type of hum

ID: 140356 • Letter: 3

Question

3. There are over 17,000 base pairs on chromosome 17 that code for a type of human collagen (COLIAI) found in many tissues, including bone (Bardai et al. 2016; International Human Genome Sequencing Consortium; map can be seen on University of California Santa Cruz genome browser, https://genome.ucsc.edu). If there are significant changes to the normal code for this collagen, it may result in problems with skeletal development and other tissues. Part of the protein sequence for this code is: CAGGGCCAGGGGGTCCCTCAGCTCCAGCCTGAGCTCCAGCCTCTCCAT Fill out the following table containing 10 of those allele codes: Complementary DNA Triplet Code Amino Acid DNA CAC GGC mRNA Code tRNA Code GTC CCT CTC CAG GAG CAT TGC

Explanation / Answer

DNA Complementary DNA triplet code mRNA tRNA Amino acid CAG GTC CAG GUC GLUTAMINE GGC CCG GGC CCG GLYCINE GGG CCC GGG CCC GLYCINE GTC CAG GUC CAG VALINE CCT GGA CCU GGA PROLINE CTC GAG CUC GAG LEUCINE CAG GTC CAG GUC GLUTAMINE GAG CTC GAG CUC GLUTAMATE CAT GTA CAU GUA HISTIDINE TGC AGC UGC ACG CYSTEINE

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