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Modern DNA sequencing clearly identifies alleles by showing the different DNA se

ID: 141062 • Letter: M

Question

Modern DNA sequencing clearly identifies alleles by showing the different DNA sequence of each allele. These alleles may be termed structural alleles (I coined the term for this problem.). Classical genetics only dealt with phenotypes or visible traits. As a result, alleles of genes were identified by functionality, usually normal or non-functional. Using your knowledge of gene structure and gene expression, postulate a relationship between structural alleles and functional alleles. (include relative amounts; more, less, or equal).

Explanation / Answer

Structural alleles when transcripted and subsequently translated shall practically give functional alleles.

For a gene coding for a certain character, the different structural alleles should code for different qualities or quantities of the same character, eg, a character for colour can code for a light colour by coding for 'less' amount of colour, in the same way, coding for a darker colour would mean coding for 'more colour'.

These different colours would be visible externally as different phenotypes and would thus be seen as different traits.

Thus, we can say that structural genes code for characters that tend to appear as functional genes externally.

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