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How does an exon-junction complex (EJC) protect the translation process from pre

ID: 141109 • Letter: H

Question

How does an exon-junction complex (EJC) protect the translation process from premature stop codons? Select the best answer.

A. EJC's are added after the splicing at each junction; although the ribosome may encounter a stop codon, if there is an EJC beyond it, the ribosome knows that there is an error

B. EJC's protect the translation process by reversibly fixing the mutated premature stop codon before the ribosome processes it (through nucleotide excision repair)

C. EJC's do not protect the translation process

Explanation / Answer

Answer:

Exon-junction complex (EJC) protect the translation process from premature stop codons because EJC's are added after the splicing at each junction; although the ribosome may encounter a stop codon, if there is an EJC beyond it, the ribosome knows that there is an error.

Hence,option(a) is correct answer.

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