Why have no true-breeding tailless Manx cats been found? How could you determine
ID: 141911 • Letter: W
Question
Why have no true-breeding tailless Manx cats been found? How could you determine if the tailless phenotype is penetrant?
untg in purplé èyes when homozygous. A female with Bar but s is mated to a male wth normal-shaped but purple eyes b. What t are the expected phenotypic ratios in the Fi generation? Show your work/reasoning. (3 pts) c. if one of the F, males is mated to an Fi female, what are the expected results in the F: generation? Show your work. (3 pts) 3. The Manx breed of cat has no tail or a very short tail. When two Manx cats are bred to each other, he litter size is reduced, some of the kittens have no tails, and some have a full-length tail. Among such crosses,tailless offspring are about twice as common as kittens with a full til. No true- breeding Manx cats have been found, despite more than a century of interest by cat breeders. a. Provide an explanation consistent with these data that explains why no true-breeding tailless Manx cats have been found. (1 pt) b. In addition to being tailless, the Manx breed is often prone to skeletal problems such as a shortened or poorly formed spinal column. Using the proper terminology, postulate an explanation for this phenotype. (2 pts)Explanation / Answer
A) In manx breed of cats the characteristic taillessness arises as a result of the dominant trait of 'manx taillessness gene' which is an outcome of spontaneous mutation.
This dominant trait expression eventually became common in the natural habitat of manx breed due to limited genetic diversity, which can be explained by the founder effect.
Thus by attempting to force the tailless manx to true-breeding by continually breeding the tailless manx with other tailless manx results in increased negative effects and even fatal genetic disorders.
Therefore, no true breeding tailless manx cats have been found.
B) the manx cats without tail and poorly formed spinal column are the results of Manx syndrome.
Manx syndrome is a genetic mutation that causes taillessness in manx cats which is a result of bad breeding genes. It also results in other complications like poorly formed spinal column, development of irregular spinal cord, lack of feeling in hind legs and various other neurological diseases.
This is also seen in other breeds of cats as in manx breed.
C) The percentage of individuals that shows a particular phenotype among those capable of showing it is known as penetrance. Since most of the offspring of true breeding between tailless manx are tailless, it shows that the dominant trait responsible for taillessness has a high degree of penetrance.
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