What will be the amount of DNA that is wrapped around the octamer and linker his

Question

What will be the amount of DNA that is wrapped around the octamer and linker histone H1 in a normal worm, and what will be the amount of DNA wrapped around the nucleosome in the mutant C. elegans?

H3 H4 H3 H4 H1 Linker H2B H2A H2B H2A Histone tails Figure A Normal Figure B: Mutant Due to an error in meiosis, the gene for linker histone H1 got deleted in a mutant Caenorhabditis elegans (figure B). Suppose that the core histones bind to 145bp, the linker DNA covers 30 bp and the linker histone binds to additional 15bp of DNA, what will be the amount of DNA that is wrapped around the octamer and linker histone H1 in a normal worm (figure A) and what will be will be the amount of DNA wrapped around the nucleosome in the mutant Caenorhabditis elegans (figure B)? O 160bp, 145bp O 145bp, 160bp O 160bp, 175bp O 175bp, 160bp

Explanation / Answer

ANSWER:

Due to an error in meiosis, the gene for linker histone H1 got deleted in a mutant Caenorhabditis elegans.
Supposing that the core histones bind to 145bp,
the linker DNA that covers 30 bp will always stay free
and the linker histone binds to additional 15bp of DNA,

Amount of DNA that is wrapped around the octamer and linker histone H1 in a normal worm = 160bp
Amount of DNA wrapped around the nucleosome in the mutant Caenorhabditis elegans = 145bp
Hence ANSWER is 160bp, 145bp

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