A. Which of the following statements is most TRUE regarding the alpha helix of a

Question

A. Which of the following statements is most TRUE regarding the alpha helix of a protein in aqueous solution as represented by the hydropathy plot shown below?

a. it lies on the surface of the protein with the right side exposed to the solvent and the left side facing the interior of the protein

b. it lies on the surface of the protein with the left side exposed to the solvent and the right side facing the interior of the protein

c. it protrudes on the outside of the protein into the solvent

d. it lies buried in the interior of the protein

B. Which arrow is pointing toward a peptide bond? a or b or c or d

Explanation / Answer

Answer A. Option b

Hydropathy plot is made to determine the hydrophobicity of a polypeptide. It is determined from N to C terminal. N terminal is on the left determines the hydrophilic region means this will be close to the solvent. Whereas the graph on the C terminal side determines the hydrophobic region means this region is acting as a transmembrane.

Answer B. Option a

Peptide bond or amide bond joins the 2 or more amino acids to form a peptide. It involves a condensation reaction between the C terminal on the left and N terminal on the right, water molecule is excluded and 2 amino acids are joined together.

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