Which of the following would NOT increase the rate of glucose uptake into liver

Question

Which of the following would NOT increase the rate of glucose uptake into liver cells?
A.Increase the concentration of glucose in the medium/blood B.Stimulate the breakdown of glycogen to glucose in the cell C.Transfect cells with the wild-type GLUT1 gene, so cells now express GLUT1 and GLUT2 D.Increase expression of GLUT2 Which of the following would NOT increase the rate of glucose uptake into liver cells?
A.Increase the concentration of glucose in the medium/blood B.Stimulate the breakdown of glycogen to glucose in the cell C.Transfect cells with the wild-type GLUT1 gene, so cells now express GLUT1 and GLUT2 D.Increase expression of GLUT2
A.Increase the concentration of glucose in the medium/blood B.Stimulate the breakdown of glycogen to glucose in the cell C.Transfect cells with the wild-type GLUT1 gene, so cells now express GLUT1 and GLUT2 D.Increase expression of GLUT2 A.Increase the concentration of glucose in the medium/blood B.Stimulate the breakdown of glycogen to glucose in the cell C.Transfect cells with the wild-type GLUT1 gene, so cells now express GLUT1 and GLUT2 D.Increase expression of GLUT2

Explanation / Answer

Ans. Option (c) is correct.

GLUT1 is mainly present in erythrocytes while GLUT2 is present in hepatocytes. So transfecting cells with GLUT1 gene would not increase the rate of glucose uptake into liver cells.

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