Answer each question in one short paragraph. Provide two peer-reviewed reference

Question

Answer each question in one short paragraph. Provide two peer-reviewed references for each answer please.

1. (a) Discuss the permeability of biological membranes as a function of hydrophilicity lipophilicity of solute molecules. (b) Discuss the permeability of biological membranes as a function of a solute molecule size. (c) What is the approximate molecular weight above which the permeation of water-soluble substances by diffusion occurs at negligible rates? (d) How dio water-soluble molecules that are much larger than this cut-off enter and leave the cell?

Explanation / Answer

A) Biological membrane are generally made of lipid. Which are fats. If any molecule is lipophilic it will easily pass through it while hydrophilic molecules will not be soluble in lipids and can't pass, means it less permeable.

B) shorter the molecular size easier the transport through the membrane as the pores or channels are small.

C) size is 3000-5000Armstrong. And molecular weight is 60kDa (kilo dalton)

D) The larger molecules are transported via facilitated or active transport via transport channels in the membrane.

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