Use the information below to answer questions 1-4. In humans, cystic fibrosis is

Question

Use the information below to answer questions 1-4. In humans, cystic fibrosis is inherited as an autosomal recessive condition whereas Huntington's disease is autosomal dominant. A normal woman with no family history of Huntington's disease but whose father had cystic fibrosis marries a man whose mother had Huntington's disease. The couple had two children, one with both cystic fibrosis and Huntington's disease and a second who had neither disease. 1. What are the genotypes of the parents? (2 pts) Mother's genotype: Father's genotype: 2. How many gamete types will each parent produce? Your answer should include the formula and calculation used to determine the number of gametes as well as a branch diagram for each parent. Use colored pencils to draw your branch diagram. (4 pts) Mother Father 3. Use the table below to draw a Punnett square showing the phenotypic and genotypic distribution expected among the progeny of the parents. 4 pts) Phenotypic ratio: Genotypic ratio:

Explanation / Answer

1:- mothers genotype : Cc

Father's genotype :- Hh

2:- mother Father

C c H h

c Cc cc h Hh hh

c Cc cc h Hh hh

Genotypic ratio :- 1Cc : 1cc

Phenotypic ratio :- 1 carrier : 1 with the disease

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