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s asked the oncologist to explai in the complete blood count (CBC) in terms that

ID: 144820 • Letter: S

Question

s asked the oncologist to explai in the complete blood count (CBC) in terms that they could understand. They had been told that a hi DH had an infection. How was the white blood cell count different in AML? The oncologist explained that DH's white blood cell count was much higher than what would he expected with an infection aone. DIi could have an infection as well, but one thing was certain -DH needed to be admitted to the hospital. She needed a complete work up of her condition, a treatment plan for oncologist nee more information, and she wasn't sure they had much time to sort this case out. I. DH has an extremely elevated white blood cell count on her most recent CBC, which is commonly found in both infections and AML. Which of the following statements is true regarding the group of cells that are collectively known as leukocytes? a. Leukocytes are much smaller than erythrocytes and have lost their nuclei during the maturation process. Leukocytes fall into one of two groups, granulocytes or agranulocytes, based on the appearance of their nuclei. Leukocytes fall into one of two groups, granulocytes or agranulocytes, based on the presence or absence of cytoplasmic granules. The granulocyte group includes the following cell types: T cells, B cells, and monocytes. b. c. d. The oncologist has confirmed the diagnosis of AML, which is a type of cancer in which the bone marrow makes abnormal myeloblasts (a white blood cell precursor), erythrocytes, or platelets. (a) Which specific group of white blood cells would you expect to be affected by AML? (Hint: Discuss the difference between the leukopoiesis of the 2.

Explanation / Answer

case1-The patient (DH) has abnormal WBC count as she is suffering from an infection. She will have an increase WBC as the body will be in a state trying to combact the infection.

In AML the WBC count may increase or decrease. In both the cases the WBC will not be properly functional hemce the body is not in aa fighting state with the disease.

2- The WBC are divided into two major types based on the presence of granules in their cytoplasm viz agranulocytes and granulocytes.

In the blood circulation, lymphocytes and monocytes are agranulocytes and neutrophils, eosinophiles and basophiles are granulocytes.