An individual gets infected by a blood-borne pathogen for the first time. Assume

Question

An individual gets infected by a blood-borne pathogen for the first time. Assume you are looking at one B cell that responds to a particular epitope from this blood-borne pathogen to answer the following questions. a. Which type of B cell (naïve, effector, memory) gets activated during this primary exposure to the pathogen? b. What does this B-cell need to become activated? c. What antibody isotype is secreted during the first 7 days of the primary response? What antibody isotype would be secreted after 10 days during the primary response?

Explanation / Answer

a. Memory B cell are activated during primary exposure.

Forms from activated B cells.

b. B cell activated by binding of antigen to the receptors on its surface which cuses cell to divide and proliferation.

c. IgM activated after primary response within 7 days and IgG appears after 10 days.

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