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QUESTION 23 Which of the following best describes how Sulfonamides acts to kill

ID: 148482 • Letter: Q

Question

QUESTION 23 Which of the following best describes how Sulfonamides acts to kill bacteria? Inhibition of cell wall synthesis Disruption of cytoplasmic membrane e Inhibition of protein synthesis Inhibition of metabolic pathways O Inhibition of DNA or RNA synthesis QUESTION 24 Which of these mechanisms would be effective in resisting the mechanisms of sulfonamides? O Alter pores to prevent drug entry into the cell O Alter target enzyme to reduce drug affinity Increase import of downstream substrates reducing dependance on the drug target O AM of the above QUESTION 25 Which of the following best describes how AZT acts to kill HIV? Inhibition of cell wall synthesis O Disruption of cytoplasmic membrane Inhibtion of protein synthesis Inhibition of metabolic pathways O Inhibition of DNA or RNA synthesis Click Save and Submit to save and submit. Click Save All Answers to save all answers e to search

Explanation / Answer

23. Inhibition of DNA or RNA synthesis. It initially inhibits Folic acid synthesis which is required for production of purines and pyrimidines.

24. All of the above. All the three mechanisms would resist a bacteria against sulfonamide.

25. Inhibition of DNA or RNA synthesis. AZT is an analogue of thymidine and inhibits the reverse transcriptase enzyme that the virus needs for replication and incorporation of its genetic material into the host cell's genome.

26. AZT disrupts the stomach causing vomitting

27. True. If the antibiotics are used improperly, for example used without cause or not used throughout the infection can select strains that can learn to survive in presence of these antibiotics. Then through natural selection these strains reproduce and multiply developing into a new resistant strains of the previous bacterial species.

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