Write out the structural formula of a peptide as described below: 1. Use the fol

ID: 148879 • Letter: W

Question

Write out the structural formula of a peptide as described below:

1. Use the following amino acids: Methionine, Valine, Serine, Glutamate.

2. Write the peptide as it would exist at pH 7 including all charges.

3. Place methionine in the N-terminal position.

4. Place Valine in the C-terminal position.

5. Place serine and glutamate in either of the remaining positions.

6. Now write out the peptide using the one letter code for each amino acid.

Hints:

•First assemble the peptide backbone, and then add the functional groups.

•Remember that peptide bond formation is a condensation reaction (dehydration synthesis).

•Remember not to use the side chains to make peptide bonds.

•Remember that acids and bases are fully charged at neutral pH.

Due to some error IN THE WEBSITE, the image cannot be uploaded.

The answer to the questions requires images but still the overall charge on the peptide

NH2----M-S-E-V---C00H is neutral at pH=7

Three peptide bonds are formed, they are strong bonds with partial double bond character.

ONE LETTER CODE FOR AMINO ACIDS:

Methionine: M , Serine: S, Glutamate : E and Valine: V

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