The ability to taste the chemical phenylthiocarbamide is an autosomal dominant p

Question

The ability to taste the chemical phenylthiocarbamide is an autosomal dominant phenotype the inability to taste the chemical is recessive. Meghan is a taster female with an She marries Harry, a taster man who had a non-taster daughter Using T for the taster allele, and t for the non-taster allele, what are Meghan and genotypes at the taster gene ? and ather in a previous, secret marriage Harry's Meghan [1 point Harry [1 point) (7) An individual with cystic fibrosis a rare, autosomal recessive disorder - has parents who are whom have cystic both un-affected. The individual with the disease has several siblings, none of fibrosis. What fraction of the individual's disease-free siblings are likely to be carriers of the disease allele? 2 points]

Explanation / Answer

6.In autosomal dominant phenotype, the presence of one dominant allele is sufficient to have the characteristic developed

Because Meghan's father was non taster which is a recessive allele so the genotype of Meghan (taster) will be Txtx.

Coming to Harry, who is a taster but has a non taster daughter.Therefore, his genotype will be Txty.

Meghan = Txtx

Harry = Txty

7) As cystic fibrosis is a autosomal recessive disease, it means both of the alleles should be recessive in order to make the person affected.Presence of one recessive allele will make the person carrier.

As the individual has cystic fibrosis , so its genotype will be cc ( "c" to denote cystic fibrosis allele )

Out of its siblings, the ones with genotype NN , Nc , cN ( "N" for normal allele) will be disease free and the ones with genotype cc will be affected with cystic fibrosis.

But out of them , the ones who have genotype Nc and cN will act as carriers.So the fraction that becomes the carrier out of disease free individuals will be 2/3.

Hope it explains your query, Good luck !!!

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