A geneticist is mapping the chromosomes of the newly captured gremlin. The strip

Question

A geneticist is mapping the chromosomes of the newly captured gremlin. The stripe is heterozygous for three linked genes with alleles Ee, Hh, and Bb, that determine if gremlins are evil (E), have hair (H), and biting teeth (B). In order to determine if the three genes are linked, a standard testcross was done, and the 1000 offspring had the following genotypes 48 36 400 4 426 46 38 2 ee Hh bb ee hh Bb ee Hh Bb Ee Hh Bb Ee hh bb Ee hh Bb Ee Hh bb Choose the alleles on the homologous chromosomes of the heterozygous individuals with the correct gene order What is the recombination frequency between genes E and B? 8.4% 9.0% 42.6% 9.4% 10.0%

Explanation / Answer

Order of the gene : H E B

Parental genome: Hh ee Bb = 400

                               hh Ee bb = 426

Note: Parental genotype will always be present in high number.

Double crossover: hh ee bb = 2

                          Hh Ee Bb = 4

Note: Double crossover event will always be present in low number.

Single cross over between H and E: hh ee Bb = 36

                                                          Hh Ee bb = 38

Single cross over between E and B: Hh ee bb = 48

                                                    hh Ee Bb = 46

Single cross over between E & B = No. of recombinant happened between E and B / Total recombinant

                                                = (48 + 46) / 1000

                                                = 0.094

                                                = 0.094 * 100 = 9.4%

Answer: 9.4%

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