Unit 2 Homework (13 of 36) Time Spent 00:00:1 13 Estrogen and testosterone are s
ID: 150376 • Letter: U
Question
Unit 2 Homework (13 of 36) Time Spent 00:00:1 13 Estrogen and testosterone are structurally related to cholesterol. Based on what you have learned about cholesterol, predict how these steroid hormones signal to the cell. Q13: A) They diffuse directly through the plasma membrane and into the cell. B They make the membrane so fluid that small pores appear, allowing them to pass through. C) They are phagocytosed, degraded, and then released into the cell. D) They bind to receptors on the outside of the membrane, which then activate an intracellular signaling cascade.Explanation / Answer
A.
Steroid hormone receptors are found in the nucleus, cytosol, and also on the plasma membrane of target cells. They are generally intracellular receptors (typically cytoplasmic or nuclear) and initiate signal transduction for steroid hormones which lead to changes in gene expression over a time period of hours to days.
Steroid hormones enter the cell by simple diffusion across the plasma membrane.
The receptors exist either in the cytoplasm or nucleus.
Once inside the cell , the steroid hormone binds with a specific receptor found in the cytoplasm of the target cell. The receptor bound steroid hormone then travels into the nucleus and binds to another specific receptor on the chromatin. Once bound to the chromatin, this steroid hormone-receptor complex calls for the production of specific RNA molecules called messenger RNA (mRNA) by a process called transcription. The mRNA molecules are then modified and transported to the cytoplasm. The mRNA molecules code for the production of proteins through a process called translation.
Related Questions
Navigate
Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.