Take Test: Problem Cystic fibrosis is a recessive genetic disorder caused by all
ID: 150635 • Letter: T
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Take Test: Problem Cystic fibrosis is a recessive genetic disorder caused by allele c. People with genotypes CC and Cc for this trait are not affected by the disease. The frequency of allele c in the human population of Eastern Siberia is 0.05 Use the Hardy-Weinberg theorem to estimate how many babies out of 1000 are born with cystic fibrosis. Oa 5 Ob. 2.5 Od.0.05 Oe. 25 Of. 4 QUESTION 2 Cystic fbrosis causes persistent lung infections and limits the ability to breathe over time. In people with CF, a defective gene causes a thick, sticky buildup of mucus in the lungs, pancreas, and other organs. The disease is often fatal. How will the frequency of allele c change over time? 0 It will not change at all from generation to generation Ob. t will increase slightly until t reaches a point of stable equilibrium OG. It will increase rapidly until t reaches 1 Od. It will fluctuate around the point of unstable equilibrium e. It will decline very slightly from generation to generation, never reaching 0 Of. it will decline rapidly until it reaches o Chek Save and Submit to save and submit, Click Suive All Ansivers to save all answers Save All Answers ClosExplanation / Answer
1. The Hardy-Weinberg equation is expressed as:
p 2 + 2pq + q 2 = 1
where p is the frequency of the "C" allele and q is the frequency of the "c" allele in the population.
Also , we know that ,
p + q =1
We have q as 0.05. Therefore p = 1-0.05 = 0.95
Now , q 2 = 0.05 x 0.05 = 0.0025.
This is the allele frequency of cc.
This means the probability of a baby with cystic fibrosis is 0.0025.
That means out of 1000 babies , 25 babies will be affected .
2.Hardy–Weinberg equilibrium, states that allele and genotype frequencies in a population will remain constant from generation to generation in the absence of other evolutionary influences .
Therefore , the allele frequency of c will remain constant.
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