Part G Why would the drug fluconazole (an azole drug) affect fungi and not human

Question

Part G Why would the drug fluconazole (an azole drug) affect fungi and not human cells? (NCLEX style) View Available Hint(s) O The drug targets fungal cell plasma membranes; because human cells lack a plasma membrane, they lack the drug's target. O The drug targets cholesterol that is present in the plasma membrane of fungi and absent in human cell plasma membranes. O The drug targets the cell wall in fungi; because human cells lack a cell wall, they lack the drug's target. O The drug targets ergosterols that are present in the plasma membrane of fungi and absent in human cell plasma membranes. Submit Part H True or False: A pharmaceutical agent designed to disrupt the function of fungal ribosomes would likely have no effect on human ribosomes. (NCLEX style) View Available Hint(s) False True Submit

Explanation / Answer

part G:

The correct answer is option 4. Drug prevents the conversion of lanosterol to ergosterol, an essential component of the fungal cytoplasmic membrane. This ergosterol is absent in animals. The same function of ergosterol carried by the cholesterol in animals.

H: answer false.

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