Q- Search in D Homework 2, proteins-Saved to my Mac ReviewView n Layout Referenc

Question

Q- Search in D Homework 2, proteins-Saved to my Mac ReviewView n Layout References Mailings to-date with security updabes, foxes, and improvements, choose Check for Updates HOH HOHHOHHOHHOHHOHHOHH H N-C-C-N-C-C-N-C-C-N-C-C-N-C-C-N-C-C-N-C-C-N-C CH ck, CH2 CH, CH, CH2 CH2 CH2 CH2 SH CH2 NH OH 'NH NH2 2. The amino acids in this polypeptide are numbered from 1-8. The following four forces/interactions determine the tertiary structure of this polypeptide. For each of the forces/interactions listed, write down the numbers of 2 amino acids that could be involved in this type of force/interaction i. ii. AND state why you think that this bond/interaction is going to occur between the two amino acids that you listed

Explanation / Answer

Hydrogen bond: Amino acid 1(Serine) and 5( Tyrosine) have hydroxyl group that helps to form hydrogen bond as they act as hydrogen bond donars.

Ionic bond: Amino acid 2 and 8 are negatively charged and due to presence of charged side chains (COO-) they can form ionic bonds.

Disulfide Bridge: Amino acid 3 and 7( Cystine) has sulfer group in their side chain and in presence of oxidized environment they form disulphid bridge.

Hydrophobic effect stabilized by Van der Waals force: Amino acid 4 and 6 show this.

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