If the sidechain of Q100 is set to the position of zero degrees on a helical whe

Question

If the sidechain of Q100 is set to the position of zero degrees on a helical wheel, at what angle would V102 point?
How long would this 12 residue helix be (in Å)?

The michaelis-menten equation is based on the initial rate approximation. What reaction is ignored when using this approximation?
If the sidechain of Q100 is set to the position of zero degrees on a helical wheel, at what angle would V102 point?
How long would this 12 residue helix be (in Å)?

The michaelis-menten equation is based on the initial rate approximation. What reaction is ignored when using this approximation?
If the sidechain of Q100 is set to the position of zero degrees on a helical wheel, at what angle would V102 point?
How long would this 12 residue helix be (in Å)?

The michaelis-menten equation is based on the initial rate approximation. What reaction is ignored when using this approximation?

The michaelis-menten equation is based on the initial rate approximation. What reaction is ignored when using this approximation?

Explanation / Answer

Hi, I the first question appears incomplete.

2. The alpha helix is 20 amino acid long. Each amino acid adds 0.15nm of length to alpha helix. so 20 amino acid = 20 * 0.15 nm = 3 nm
in angstom = 30 A.

3. Michalis menton equation is based on initial rate approximation. This approximation is that in the plot of S v/s V, as the S increases to much larger amount, the V approaximates to a maximal value limit. That is it does not increase infinetely. In the equation V= V,max [S]/ (ks + [S))
The value S and Ks. S do not have large difference, so [S]is nearly equal to [ks+[S]]. Hence the equation changes to
Vo= Vmax. [S] / Ks.

This is the approximation of the michaelis menten equation.

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