Joan is phenotypically normal, but had a child with the autosomal recessive dise

Question

Joan is phenotypically normal, but had a child with the autosomal recessive disease cystic fibrosis (CF) from a previous marriage. Joan's father has hemophila A, a sex-linked recessive condition where the blood fails to clot properly. Her father has survived due to recent treatment advances. Joan now intends to marry Bill, who is also phenotypically normal but who has a sister, Jill, with CF. Bill's parents are phenotypically normal, and there is no history of hemophilia A in his family. Assume that Joan and Bill do marry and have a child. What is the probability that this child will have CF, but will not have hemophilia A?

Explanation / Answer

The answer is =

probability that this child will have CF, but will not have hemophilia A=>

Probabiliy of having CF X Probability of having Hemophilia C X probability of being normal=>

1/2X1/2X1/2=1/8

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