Which of the following mechanisms would NOT contribute to cancer cell transforma

Question

Which of the following mechanisms would NOT contribute to cancer cell transformation? A. Erosion of telomeric DNA B. Regeneration of telomeric DNA through the ALT mechanism C. Repeated breakage-fusion-bridge (BFB) cycles D. Stabilization of telomeres E. Increased expression of telomerase 1. 2. Which of the following be advantageous for the survival of a cancer cel? A. An inactivating mutation in a tumor suppressor gene B. An inactivating mutation in an oncogene C. An inactivating mutation in a gene that promotes apoptosis D. Methylation of the promoter of a tumor suppressor gene E. B and D I5

Explanation / Answer

1.A.

Erosion of telomeric DNA

2.B.

an inactivating mutation in an oncogene

This will not be advantageous mutation for survival of a cancer cell.

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