1) When nitric oxide is used in the dilation of smooth muscle cells, which of th

Question

1) When nitric oxide is used in the dilation of smooth muscle cells, which of the following would interfere with the relaxation of the smooth muscle cells? Inhibitors of
A) calcium release by the ER.
B) nitric oxide.
C) guanylyl cyclase.
D) calmodulin.
E) all of the above


3) All of the following are second messengers except
A) calcium ions.
B) IP3.
C) DAG.
D) cameleons.
E) PDGF.


5) Hydrophobic messengers include which of the following?
A) retinoids
B) cAMP
C) pertussis toxin
D) calcium ions
E) ryanodine

7) Which of the following would be characterized as a juxtacrine signal?
A) contact-dependent
B) endocrine
C) self-responding
D) distal neighbors
E) both choices B and D


9) Which of the following ligands would not have an intracellular receptor?
A) cortisol
B) retinoic acid
C) thyroxine
D) epinephrine
E) progesterone

Explanation / Answer

The first source of NO identified, endothelial NO synthase was the last to be cloned and is known as eNOS or NOS3. NOS3 binds to plasma membranes and is typically associated with caveolin (387). It is strongly activated by the entry of calcium through membrane-bound receptors and is also regulated by phosphorylation

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