In studies of the amino acid sequence of wild-type and mutant forms of tryptopha

Question

In studies of the amino acid sequence of wild-type and mutant forms of tryptophan
synthetase in E. coli, the following changes have been observed:
gly-->arg-->thr
gly-->arg-->ser
gly-->arg-->ile
gly-->glu-->val
gly-->glu-->ala


Determine a set of triplet codes (i.e. codons for each amino acid) in which only a single nucleotide change produces each amino acid change. Refer to (http://zlgc.seu.edu.cn/jpkc/2010jpkc/jykc2/content/jxzy/genetics/chapt08/art_library/color_art_library/08_03.jpg) for the DNA sequences of the codons for each amino acid.

Explanation / Answer

The set of triplet codons for the point mutations are:

gly-->arg-->thr:
GGG--->AGG---->ACG
gly-->arg-->ser:
GGG--->AGG---->AGU
gly-->arg-->ile:
GGA--->AGA---->AUA
gly-->glu-->val:
GGG--->GAG---->GUG
gly-->glu-->ala:
GGG--->GAG---->GCG

Related Questions

Navigate

• Browse (All)
• Browse I
• Subjects

---

---

Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.