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Which is the extracellular face of this image? (Top or Bottom) what is your evid

ID: 162204 • Letter: W

Question

Which is the extracellular face of this image? (Top or Bottom) what is your evidence for this? What are the macromolecules represented in boxes A & B? Distinguish using formal terms the difference between that in box A versus that in box B. How does the presence of A in the membrane, compared to B, affect membrane function? Distinguish using formal terms the difference between protein C and protein D. What intermolecular interactions exist between C and membrane molecules such as A and B? What molecule is represented by E?

Explanation / Answer

1. Top face shows extracellular membrane as it interacts with environment and bottom interacts with cytoplasm, so it is inside called as intracellular.

2. A box shows unsaturated phospholipid (it has a kink in a structure)
B box shows saturated phospholipid ( it don't have any kink).

3. Box A has kink so there is resistant in membrane fluidity, so molecules has difficulty in entery or exit because of kink
This is not the case of box B as it shows easy fluidity.

4. C shows transmembrane protein and D is peripheral protein

Peripheral membrane proteins, or extrinsic proteins, do not interact with the hydrophobic core of the phospholipid bilayer. Instead they are usually bound to the membrane indirectly by interactions with integral membrane proteins or directly by interactions with lipid polar head groups.

Transmembrane protein (TP) is a type of integral membrane protein that spans the entirety of the biological membrane to which it is permanently attached. Many transmembrane proteins function as gateways to permit the transport of specific substances across the biological membrane.

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